Korean researchers mix two processes 3D prints human skin-EBY

                       EBY
It is reported that South Korea's Pohang University of Science and Technology researchers to develop an efficient, low-cost method to 3D print can be used to repair the operation of human skin. Their hybrid cell 3D printing system consists of two modules for extrusion and jetting.
In a recent paper published in Biofabrication, the researchers explained how they developed a hybrid 3D printer that uses two different 3D printing methods and a polycaprolactone (PCL) membrane. Make a skin-based, collagen-based material. They believe that this new system can better print the skin compared to existing methods.
The secret of this new 3D printer is that it uses two deposition methods: extrusion and injection. The printer uses both extrusion and jetting modules, allowing the researcher to use a PCL film to create collagen-based materials. The combination of these two substances produces something very similar to human skin.
"PCL is a biodegradable polyester that prevents collagen from contracting during tissue maturation," the researchers explained. "At the same time, we use a spray-based dispensing module that combines keratinocytes (the most important Of the cell type) evenly distributed to the artificial skin.                        
The team has produced a 3D print skin model that can mature without the use of commercial cell culture inserts. After 14 days, the model also showed impressive biological features, including a stable, fibrous cell stretched dermis and stratified epidermis.
The research team said that compared with other technologies, this 3D printing method has some other outstanding advantages. "It is important that our new method is 50 times cheaper than other methods and requires 10 times less base material.We hope that this new single-step process can provide an attractive and useful for making full-featured human skin models Platform, "the researchers said.
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